Abstract

Analyzed 2 deaths from pathological and forensic practice in order to show that comorbid diseases in young patients in the context of the COVID-19 pandemic increase the risk of an adverse outcome due to the potentiation of the systemic damaging action of the viral agent, decompensation of chronic therapeutic pathology, the development of acute complications and status, possible drug interactions. The management of this category of patients requires knowledge of the characteristics of a viral infection, its clinical manifestations in combination with comorbid diseases.

Highlights

  • Analyzed 2 deaths from pathological and forensic practice in order to show that comorbid diseases in young patients in the context of the COVID-19 pandemic increase the risk of an adverse outcome due to the potentiation of the systemic damaging action of the viral agent, decompensation of chronic therapeutic pathology, the development of acute complications and status, possible drug interactions

  • В контексте иммунодефицита, который был указан как сопутствующее состояние в основном клиническом диагнозе, особенно стоит отметить наличие лимфопении, а также снижение показателей каждого типа лимфоцитов на порядок ниже нормы по результатам иммунологического обследования, что отмечается в ряде случаев у пациентов с COVID-19 [6]

  • Патоморфологические особенности поражения органов при коронавирусной инфекции, вызванной SARS-CoV-2 // Волгоградский научно-медицинский журнал

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Summary

Introduction

Analyzed 2 deaths from pathological and forensic practice in order to show that comorbid diseases in young patients in the context of the COVID-19 pandemic increase the risk of an adverse outcome due to the potentiation of the systemic damaging action of the viral agent, decompensation of chronic therapeutic pathology, the development of acute complications and status, possible drug interactions. Что иммунодефицит повышает как риск инфицирования SARS-CoV-2, туберкулеза, способствует тяжелому течению заболевания [1, 2, 3, 8].

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