Open Access
24- https://doi.org/10.1007/s40506-021-00249-6
COVID-19 in Solid Organ Transplant Recipients: a Review of the Current Literature.
Translate Article 
Take Notes Purpose of reviewThe approach to ongoing organ transplantation and management of COVID-19 in solid organ transplant recipients (SOTR) has evolved tremendously since the pandemic’s beginning. We summarize the current literature surrounding the virology of SARS-CoV-2, epidemiology of COVID-19 in transplant recipients, review the clinical features and complications of COVID-19 in SOTR, and discuss the safety and efficacy of current therapies and candidate vaccines in this population.Recent findingsDespite initial suspensions in organ transplantation during early 2020, routine donor testing and de-crowding of hospitals have allowed transplant activity to resume at pre-pandemic rates. COVID-19-associated mortality in SOTR is similar to that of the general population, and lower than that of patients with end-organ disease awaiting transplant. The optimal approach to immunosuppression in SOTR with COVID-19 is unknown and disease severity may influence management decisions. Many vaccines in development are likely to be safe for immunocompromised hosts, though post-marketing investigations will be required to determine the efficacy in the SOTR.SummaryThough there are multiple unique considerations in the care of SOTR with COVID-19, immunosuppression does not appear to have a detrimental impact on overall outcome. Organ transplantation remains a lifesaving intervention and can be safely performed despite a global pandemic.
- Research Article
- 44
- 10.1111/ajt.12125
- Mar 1, 2013
- American Journal of Transplantation
Travel Medicine and Transplant Tourism in Solid Organ Transplantation
- Research Article
- 123
- 10.1111/j.1600-6143.2009.02910.x
- Dec 1, 2009
- American Journal of Transplantation
Invasive Aspergillosis in Solid Organ Transplant Recipients
- Research Article
- 12
- 10.1111/ajt.15826
- Mar 10, 2020
- American Journal of Transplantation
A multicenter study to define the epidemiology and outcomes of Clostridioides difficile infection in pediatric hematopoietic cell and solid organ transplant recipients.
- Research Article
- 41
- 10.1111/ajt.16541
- May 6, 2021
- American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Prevalence and predictors of SARS-CoV-2 antibodies among solid organ transplant recipients with confirmed infection.
- Research Article
- 191
- 10.1111/ajt.12115
- Mar 1, 2013
- American Journal of Transplantation
Aspergillosis in Solid Organ Transplantation
- Research Article
- 68
- 10.1111/ajt.16431
- Feb 21, 2021
- American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Inpatient COVID-19 outcomes in solid organ transplant recipients compared to non-solid organ transplant patients: A retrospective cohort.
- Research Article
- 64
- 10.1111/ajt.16079
- Jul 17, 2020
- American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Clinical outcomes and serologic response in solid organ transplant recipients with COVID-19: A case series from the United States.
- Research Article
- 41
- 10.1053/j.ajkd.2020.12.003
- Jan 1, 2021
- American journal of kidney diseases : the official journal of the National Kidney Foundation
Practicing With Uncertainty: Kidney Transplantation During the COVID-19 Pandemic
- Research Article
- 25
- 10.1046/j.1365-2141.2002.03887.x
- Nov 18, 2002
- British Journal of Haematology
Prevention and treatment of epstein–barr virus‐associated lymphoproliferative disorders in recipients of bone marrow and solid organ transplants
- Research Article
- 30
- 10.1111/ajt.15605
- Oct 28, 2019
- American Journal of Transplantation
Underimmunization of the solid organ transplant population: An urgent problem with potential digital health solutions.
- Research Article
- 10
- 10.1111/ajt.16942
- May 1, 2022
- American Journal of Transplantation
Mortality in solid organ transplant recipients with COVID-19: More than meets the eye
- Research Article
- 20
- 10.1111/j.1600-6135.2004.00734.x
- Oct 1, 2004
- American Journal of Transplantation
Community-acquired respiratory viruses
- Research Article
- 187
- 10.1016/j.jhep.2021.01.032
- Feb 6, 2021
- Journal of hepatology
EASL position paper on the use of COVID-19 vaccines in patients with chronic liver diseases, hepatobiliary cancer and liver transplant recipients
- Research Article
- 1
- 10.5005/japi-11001-0037
- Jul 1, 2022
- Journal of the Association of Physicians of India
Post-transplant diabetes mellitus (PTDM) is a common problem among solid organ transplant recipients contributing to morbidity and affecting patient as well as graft survival adversely. It can occur at any period following transplantation, but maximum incidence is observed in the first few months, with a second peak after a few years after transplantation. The pathogenesis is complex and poorly understood, however, it is associated with both dysfunctional beta-cells and insulin resistance. Both nonpharmacologic and antidiabetic therapies are important for adequate glycemic control. This point of view article provides a short review on PTDM in solid organ transplantation (SOT) recipients from a general physician's perspective.
- Research Article
- 102
- 10.1111/ajt.15928
- May 4, 2020
- American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Clinical characteristics and immunosuppressant management of coronavirus disease 2019 in solid organ transplant recipients.
- Ask R Discovery
- Chat PDF
AI summaries and top papers from 250M+ research sources.
