Abstract
Coronavirus disease 2019 (COVID-19), a fatal virus caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a pandemic across the world. Despite early concerns, children appear to be less susceptible to acquiring SARS-CoV-2 and manifest minor clinical symptoms compared with adults. However, there still exists a risk of physical and psychological health problems in children and their families. In this review, we summarize the existing information about the mechanism of SARS-CoV-2 infection, the epidemiology of COVID-19, and the clinical manifestations, treatments, and further considerations regarding COVID-19 in children.
Highlights
In December 2019, Wuhan received worldwide attention by reporting the first case of COVID-19 in China [1]
In response to the increasing seriousness of COVID-19 as a threat to human health, researchers continue to pursue effective strategies to mitigate the physical and psychological damage due to SARS-CoV-2 infection in children and families. If children or their parents become sick with COVID-19, following guidance from local agencies and the World Health Organization (WHO) can reduce viral spread and foster a healthy environment for families
Kawasaki disease (KD) and COVID-19 are epidemiologically similar: KD is primarily distributed in East Asia, followed by Western Europe, North America, and other lower middle income countries (LMICs) such as Latin America, while COVID-19 was first reported in China and spread all over the world, of which Western Europe and North America are the worst-hit areas nowadays
Summary
In December 2019, Wuhan received worldwide attention by reporting the first case of COVID-19 in China [1]. A report from the Chinese Center for Disease Control and Prevention found that as of mid-February, among the 72,000 Chinese patients infected with SARS-CoV2,
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