Abstract

Context: A cluster and increase in pneumonia cases with unknown cause were detected in Wuhan, Hubei province, China, in December 2019. These cases were reported to be associated with a new coronavirus type by the Chinese health authorities on January 7, 2020. The first case in Turkey was diagnosed on March 11, 2020. COVID-19 (SARS-CoV-2 infection) guide was prepared for the pandemic by the Ministry of Health scientific committee. However, despite strong clinical, laboratory and radiological suspicions, there are also patients who do not meet the exact case definition. Case report: In this case report, we aimed to discuss two cases that did not meet the definitive case definition and followed up in our clinic. Conclusions: Although gold standard method for the definitive diagnosis of SARS-CoV-2 infection is PCR, rapid antibody tests and CT findings are used in combination with PCR for a more effective struggle in the pandemic process would enhance rapid diagnosis of cases, necessary treatment and isolation measures to prevent transmission. It is thought that it would be useful to make case definitions.

Highlights

  • Coronaviruses are common among humans, mammals and birds; enveloped ribonucleic acid (RNA) viruses that cause respiratory, enteric, hepatic and neurological diseases

  • Context: A cluster and increase in pneumonia cases with unknown cause were detected in Wuhan, Hubei province, China, in December 2019

  • These cases were reported to be associated with a new coronavirus type by the Chinese health authorities on January 7, 2020

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Summary

Conclusions

Gold standard method for the definitive diagnosis of SARS-CoV-2 infection is PCR, rapid antibody tests and CT findings are used in combination with PCR for a more effective struggle in the pandemic process would enhance rapid diagnosis of cases, necessary treatment and isolation measures to prevent transmission. It is thought that it would be useful to make case definitions. Key words (MeSH terms): severe acute respiratory syndrome corona virus 2; corona virus Pandemics. Authors’ key words: rapid antibody test; coronavirus disease 2019; antibody test kit

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