Abstract
A 72-year-old male was brought to the hospital following a motorcycle crash and was admitted for multiple trauma management. His initial course of hospitalization was complicated by mild hypoxemia and altered mental status. Respiratory workup and imaging were consistent with SARS-CoV-2 pneumonia. He completed a five-day course of remdesivir and a ten-day course of dexamethasone. Twenty days later, he developed a low-grade fever. His chest computerized tomography (CT) showed gas and fluid containing parenchymal collection in the anteromedial right middle lobe measuring up to 4.8 cm, most consistent with a pulmonary abscess. Antimicrobial treatment was started.
Highlights
Bacterial and fungal superinfections are common complications of viral pneumonia
The following report summarizes a case of COVID-19-associated pulmonary aspergillosis (CAPA); IRB #20.0225
Among patients with probable CAPA, those treated with voriconazole trended towards a lower mortality.[15]. These results demonstrate the need for treatment of CAPA when clinically suspected
Summary
Bacterial and fungal superinfections are common complications of viral pneumonia. The incidence varies between hospitals. Chest tightness but developed labored breathing with increased oxygen requirements His mental status continued to decline over the following two days, it was thought to be due to hypoxemia. He was admitted to the intensive care unit (ICU) and started treatment with 200 mg remdesivir, followed by a fourday course of 100 mg remdesivir along with 6 mg of dexamethasone daily for a total of 10 days The patient completed his anti-COVID-19 regimen and was weaned to high-flow O2 via an oxygen mask. A repeat chest X-ray showed bibasilar infiltrates His hospital course was complicated by a persistent fever, which in turn increased the suspicion of hospitalacquired pneumonia. Outpatient follow-up was recommended to reassess the need for antifungal medications
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