Abstract

Patients with severe coronavirus disease (COVID-19) may have COVID-19–associated invasive mold infection (CAIMI) develop. We report 16 cases of CAIMI among 146 nonimmunocompromised patients with severe COVID-19 at an academic hospital in Santiago, Chile. These rates correspond to a CAIMI incidence of 11%; the mortality rate for these patients was 31.2%.

Highlights

  • Patients with severe coronavirus disease (COVID-19) may have COVID-19–associated invasive mold infection (CAIMI) develop

  • Invasive mold infection is a serious complication described in patients with severe viral pneumonia [1]

  • The European Confederation on Medical Mycology and the International Society on Human and Animal Mycology published the diagnostic criteria for COVID-19–associated invasive pulmonary aspergillosis (CAPA), on the basis of histology, microbiology, imaging reports, and clinical factors [9]

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Summary

Introduction

Patients with severe coronavirus disease (COVID-19) may have COVID-19–associated invasive mold infection (CAIMI) develop. Invasive mold infection is a serious complication described in patients with severe viral pneumonia [1]. Centers in Europe, China, and the United States have reported cases of fungal superinfections among patients with severe coronavirus disease (COVID-19).

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