COVID-19 Aortitis: A Review of Published Cases.

Falah Abu Hassan,Ashish Nepal,Minas Abu Alhalawa,Sareen S Sufan,Yacoub Majdoubeh

doi:10.7759/cureus.22226

Abstract

Coronavirus disease 2019 (COVID-19) has a myriad of different presentations and various complications. Aortitis is one of the less explored pathologies associated with COVID-19 infections. In this review, we searched PubMed/Medline, Web of Science, Google Scholar, and Scopus for case series and case reports involving adults patients who presented with aortitis and COVID-19. We found and reviewed four published case reports of aortitis in a setting of COVID-19 infection. The mean age of the four adult patients was 69 ± 1.732 years (range = 63-71 years), and all patients were males. Most of the patients (75%) did not have any preexisting comorbidities. All patients were treated conservatively and recovered with excellent outcomes.

Highlights

BackgroundA novel coronavirus, first reported in Wuhan, China, on December 31, 2019, emerged to become a global pandemic, as declared by the World Health Organization (WHO) in March 2020
According to the Centers for Disease Control and Prevention, the illness caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can manifest in different organ systems, with a severity ranging from a mild to life-threatening illness
Pyogenic aortitis caused by Salmonella and Staphylococcus aureus infections is the most common form of infectious aortitis, whereas non-infectious aortitis includes Takayasu arteritis and giant cell arteritis [2]

Summary

Introduction

A novel coronavirus, first reported in Wuhan, China, on December 31, 2019, emerged to become a global pandemic, as declared by the World Health Organization (WHO) in March 2020. According to the Centers for Disease Control and Prevention, the illness caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can manifest in different organ systems, with a severity ranging from a mild to life-threatening illness. In 2020, coronavirus disease 2019 (COVID-19) was the third leading cause of death in the United States [1]. Aortitis is a pathologic term referring to all infectious and non-infectious conditions that lead to the inflammation of the aortic wall [2]. Pyogenic aortitis caused by Salmonella and Staphylococcus aureus infections is the most common form of infectious aortitis, whereas non-infectious aortitis includes Takayasu arteritis and giant cell arteritis [2]

Methods

Discussion

Conclusion