Abstract
COVID-19 Antibody Testing of Patients Admitted to the ICU by A Novel, Point-of-Care Assay, and the Relationship to Survival
Highlights
The COVID-19 pandemic is a major burden to the society
The IgG antibodies bound to the particles were detected by anti-human IgG and the signal expressed as nano Coulomb (nC)
Plasma (n=211) from 117 SARS-Cov-2 PCR positive patients and from 78 persons with samples taken before the COVID-19 pandemic were analysed
Summary
The AgPlus electrochemical technology was applied and the S1 and S2 proteins were biotinylated and immobilized onto streptavidin coated magnetic particles as the capture component of the assay. The IgG antibodies bound to the particles were detected by anti-human IgG and the signal expressed as nC (nano Coulomb).
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