Abstract

Diabetes mellitus (DM) is one of the most common comorbid conditions in persons with COVID-19 and a risk factor for poor prognosis. The reasons why COVID-19 is more severe in persons with DM are currently unknown although the scarce data available on patients with DM hospitalized because of COVID-19 show that glycemic control is inadequate. The fact that patients with COVID-19 are usually cared for by health professionals with limited experience in the management of diabetes and the need to prevent exposure to the virus may also be obstacles to glycemic control in patients with COVID-19. Effective clinical care should consider various aspects, including screening for the disease in at-risk persons, education, and monitoring of control and complications. We examine the effect of COVID-19 on DM in terms of glycemic control and the restrictions arising from the pandemic and assess management of diabetes and drug therapy in various scenarios, taking into account factors such as physical exercise, diet, blood glucose monitoring, and pharmacological treatment. Specific attention is given to patients who have been admitted to hospital and critically ill patients. Finally, we consider the role of telemedicine in the management of DM patients with COVID-19 during the pandemic and in the future.

Highlights

  • Hyperglycemia information on the safety and efficacy of these protocols and their application is lacking [65]. While waiting for these strategies to be evaluated, and faced with the urgent need to implement effective approaches to glycemic control in hospitalized patients with COVID-19, we recently proposed a series of recommendations on management of hyperglycemia in the critical setting and noncritical care setting, taking into account factors such as the need to prevent staff exposure and the fact that many health professionals caring for patients with COVID-19 may be relatively unfamiliar with management of hyperglycemia [65]

  • In order to minimize the consequences of this situation, it is necessary to guarantee that patients receive efficient clinical care that takes into account various services, including screening for the disease in at-risk persons, education, and monitoring of control and complications at face-to-face or remote visits as well as adaptation of treatment of Diabetes mellitus (DM) in the setting of COVID-19

  • Diabetes is one of the most common comorbidities linked to COVID-19, and there is consistent evidence that diabetes increases the risk of severe COVID-19 disease, including admission to the intensive care unit and death

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Summary

Diabetes and COVID-19

Diabetes mellitus (DM) is a medical condition that can have a considerable impact on affected persons and on society owing to the high costs associated with its care, especially those arising from complications. In addition to the direct effects on health, the absence of regular care owing to closure of outpatient clinics and social isolation—combined with changes in diet, physical activity, and personal care—favors deterioration of disease control and hampers detection of complications. This study examines the impact of the COVID-19 pandemic on persons with DM and covers implications for health in the short and long terms. It examines how to address the threat to persons with DM arising from more limited health services and changes in lifestyle resulting from the pandemic

Impact of Diabetes on COVID-19
Impact of COVID-19 on Diabetes
Effects of COVID-19 on Glycemic Control
Effects on Diabetes of the Restrictions Arising from the COVID-19 Pandemic
Diabetes Patients without COVID-19
Patients with Diabetes and COVID-19 Who Have Not Been Admitted to Hospital
Objectives of Glycemic Control
Glucose Monitoring
Pharmacologic Treatment
Control of Other Cardiovascular Risk Factors
Special Considerations in T1D
Hospitalized Patients with Diabetes and COVID-19
Management of Hyperglycemia in Critically Ill Patients with COVID-19
Management of Hyperglycemia in Non-Critically Ill Patients with COVID-19
Glucose Monitoring of Patients with COVID-19 in Hospital
Care of Patients with Diabetes during the COVID-19 Pandemic and Afterwards
Findings
Conclusions

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