Abstract
Like other respiratory viruses, COVID-19 has extrapulmonary manifestations. The effect of the virus leads to the cardiovascular system (CVS) damage in particular, which pathophysiological mechanisms are not fully understood. In this article we analyze modern ideas about COVID-19, consider possible links of pathogenesis, make an attempt to systematize pathophysiological mechanisms of cardiovascular impairment and its complications, analyze the relation with cardiovascular comorbidity, describe pathomorphological features and discuss possible long-term prognosis. The information in this article can contribute to understanding the two-way interaction of cardiovascular diseases and the effects of COVID-19 in order to develop effective preventive measures and make the right decision in choosing therapeutic tactics for a patient.
Highlights
Ключевые слова: COVID-19, SARS-CoV-2, сердечно-сосудистая система, сердечно-сосудистые заболевания, ангиотензинпревращающий фермент 2 (АПФ2), патофизиология, патоморфология, коморбидность, осложнения, долгосрочный прогноз
Долгосрочные исследования и наблюдения пациентов позволят разработать превентивные меры и тактику лечения поражения сердечно-сосудистой системы при COVID-19
COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives
Summary
Петриков С.С., Иванников А.А., Васильченко М.К., Эсауленко А.Н., Алиджанова Х.Г.
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More From: Russian Sklifosovsky Journal "Emergency Medical Care"
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