Abstract

A total of 74 COVID-19 diabetic patients were enrolled in the study. Twenty-seven patients (36.5%) were severely ill, and ten patients (13.5%) died. Severe patients had higher blood glucose, serum amyloid A (SAA), C reactive protein, and interleukin 6 levels than non-severe patients (P> 0.05). Severe patients had lower levels of albumin, cholesterol, high density lipoprotein, small and dense low density lipoprotein, and CD4 T lymphocyte counts than non-severe patients (P > 0.05). Reduced CD4 21 + T lymphocyte counts (OR = 0.988, 95 percent confidence interval [95 percent CI] 0.979–0.997) and elevated SAA levels (OR = 1.029, 95 percent CI 1.002–1.058) were found as risk variables for COVID- 19 severity with diabetes in a logistic regression analysis (P > 0.05).
 Keywords: COVID-19, Diabetes, Hyperglycemia, Dislipidemia, CD4+ T lymphocyte , follow up symptoms.

Highlights

  • Type 2 diabetes is a chronic condition that develops when the pancreas is unable to produce enough insulin or when the body's tissues are unable to adequately utilize insulin

  • This study looked at the clinical characteristics of COVID-19 patients with type 2 diabetes who were hospitalized at Zhongnan Hospital of Wuhan University in Wuhan, China, and looked at risk variables linked to COVID-19 severity in diabetics

  • According to the previous research, the 99 patients of COVID-19 admitted to Jinyintan Hospital in Wuhan 9 were mostly male (68.0 percent), with a median age of 55.5 years, a 23 percent ICU requirement, and an 11 percent fatality rate

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Summary

Introduction

Type 2 diabetes is a chronic condition that develops when the pancreas is unable to produce enough insulin or when the body's tissues are unable to adequately utilize insulin. Insulin is a hormone that aids the utilization of sugar (glucose) for energy by the body's cells. It aids in the storage of excess sugar in the body's muscle, fat, and liver cells [1]. China has diagnosed 84,250 cases in total, including 4642 deaths. Pneumonia, caused by a variety of infections, has become an increasingly common cause of death in diabetics. Clinical aspects of COVID-19 in diabetics, severe cases, have sparked widespread concern [3]

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