Abstract
The purpose of this bibliographical review is to provide an exceptional and up-to-date overview of COVID-19 infection in children describing its epidemiology, pathogenesis, clinical features and outcomes. The article provides a comprehensive analysis of publications by foreign and Russian authors on a new coronavirus infection (COVID-19) caused by SARS-CoV-2 in children. A complete clinical description of the course of COVID-19 in pediatric population is given: from asymptomatic virus carrying till the development of acute pneumonia, multi-inflammatory syndrome, multiple organ failure and death. Among the clinical manifestations there are described as follows: respiratory syndrome, gastrointestinal tract injury, manifestations in the central nervous system, lesions of the skin and mucous membranes and a complete characteristic of multi-inflammatory syndrome. The studied methods of development of COVID-19 are examined in pathogenesis. The issues of anti-tuberculosis vaccination, the impact of serum cholecalciferol level on the severity and outcomes of COVID-19 disease are highlighted. The latest publications on intrauterine infection of the fetus and the breast milk research for the presence of SARS-CoV-2 were analyzed.
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