Abstract

Influenza vaccination has been shown to be the most effective preventive measure to reduce influenza virus infection and its related morbidity and mortality. Young children aged 6–59 months are recommended as one of the priority groups for seasonal influenza vaccination in China. Our study was conducted to evaluate the level of influenza vaccination coverage during 2014–15 and 2015–16 influenza seasons among kindergarten children aged 2–7 years in Xining, a low-income city of north-western China, and to explore potential factors for noncompliance associated with influenza vaccination. The coverage rate of influenza vaccination was 12.2% (95 CI: 10.6–14.2%) in 2014–15 and 12.8% (95 CI: 11.1–14.7%) in 2015–16. The low coverage rate was found to be primarily associated with the lack of knowledge about influenza vaccine in children’s parents. The most common reason for vaccine declination was the concern about adverse reactions of vaccine. Therefore tailored information should be provided by clinician and public health doctors for targeted groups through effective methods to improve public understanding of vaccination.

Highlights

  • Influenza infection and incidence are usually highest in kindergarten and school-age children in prevalent season[1, 2]

  • The past coverage rate of seasonal influenza vaccination has been less than 10% among the children in Xining City based on quantity of the vaccines sold every year

  • Previous studies found that the policy of free vaccination could increase vaccination coverage rates[20, 21]

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Summary

Introduction

Influenza infection and incidence are usually highest in kindergarten and school-age children in prevalent season[1, 2]. In mainland China, “kindergarten” is a place to provide daycare, preschool and kindergarten education for children 2 to 7 years old before the primary school. There will be 10 to over 20 children stay in a classroom playing and learning together in a kindergarten. Due to high titers of antibody in the nasopharyngeal mucosa of infected children [3, 4] and high social contact rates[5], kindergarten and school-age children might play an important role in introducing and further transmission of influenza viruses in households and community[6]. As a study in Beijing reported, peaks of influenza-like illness.

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