Abstract
A novel modified Box ligand was applied to an asymmetric trifluoroalkylation reaction with excellent yields and ee values. The crucial effect of the ligand was based on the steric hindrance of the 3,5‐substitued aromatic ring adjacent to nitrogen atom. The construction for CF3‐substitued stereocenter on unactived spots would be a great worth in synthesis, which delivered corresponding pharmaceutically and biologically active products. More details are discussed in the article by Wang et al. on page 1531—1536.image
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