Abstract
A powerful combination of two synthetic methods has advanced the art of organic synthesis like few other reactions. In their Reviews on page 4442 ff. and 4490 ff. K. C. Nicolaou and co-workers illustrate how palladium-catalyzed cross-couplings and metathesis-based reactions, respectively, have blossomed into powerful tools for carbon–carbon bond formation in the total synthesis of natural products.
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