Abstract
An iron–catalyzed [2+1+1+1]–annulation strategy was used for the construction of five–membered maleimides, which are building blocks for naturally occurring himanimides A and B. In their Communication on page 2173 ff., M. Beller et al. report that the syntheses of himanimide A and B are conveniently achieved in only 4 and 5 steps from commercially available starting materials, respectively. Whilst himanimide B was prepared for the first time, the synthesis of himanimide A has been significantly improved with respect to overall yield. This synthetic strategy can be applied to other related bio–active compounds, such as camphorataimides, antrocinnamomins, polycitrins, and arcyriarubins.
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