Cover Picture: Heterochromia in Designed Metallopeptides: Geometry-Selective Binding of CdII in a De Novo Peptide (Angew. Chem. Int. Ed. 35/2007)

Abstract

Heterochromia is a genetic condition that causes individuals to have eyes of different colors. In the same way, nearly identical metal-binding sites in heterochromic peptides, an example of which is presented by V. L. Pecoraro and co-workers in their Communication on page 6688 ff., display different physical properties after metal binding. The cover picture shows a de novo designed heterochromic peptide that binds two CdII ions, each with a different coordination geometry.