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Abstract
The cover image of this issue consists of confocal images of c-Maf localization in HEK293 T cells, taken from Lin et al. (pp. 1174–1184). In this article, the authors examine regulation of c-Maf function by SUMOylation. The authors show that c-Maf colocalizes with SUMO (small ubiquitin-like modifier) ligases; SUMOylation attenuates c-Maf transcriptional activity, and subsequently, IL-4 expression.
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