Abstract
Mass spectrometric methods are on the march in competitive binding studies. In pharmacological research these studies are widely used to characterize ligand–target interactions. However, they usually require the use of radioligands. Now, with the aid of mass spectrometry, it is possible to use native markers instead of radioligands. This method and its use in a binding study on dopamine D1-receptors are described in the Communication by G. Höfner and K. T. Wanner on page 5235 ff.
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