Abstract
Sylite, a short, dimerized peptide-based fluorescent probe, binds gephyrin, a hallmark protein of the inhibitory synapse. As reported by Christian G. Specht, Hans M. Maric et al. in their Research Article (e202202078), Sylite visualizes inhibitory synapses both in neuron cultures and brain tissue and can be flexibly applied for widefield and confocal 3D volumetric synapse visualization, for brain tissue inhibitory circuits mapping and for super-resolution imaging of synapses. The cover picture shows a stylized image of a mouse hippocampus in coronal section stained with Sylite in green and DAPI nuclear stain in blue. Cover design by Christian Günther.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
