Cover Picture: A Stepwise Annulation for the Transformation of Cyclic Ketones to Fused 6 and 7‐Membered Cyclic Enimines and Enones (Chin. J. Chem. 4/2019)

Abstract

The cover picture shows a typical building within the Campus of Xiamen University displaying Chen Jiageng (Tan Kah Kee)'s style. Just like many beautiful buildings designed and constructed by human, Nature “designs and constructs” a huge number of useful molecules with fascinating structures called natural products. Many natural products possess a fused six or seven‐membered carbocyclic unity. On page 315–322, the Huang's group disclosed a three‐step “[2+n]” annulation method for the construction of fused six and seven‐membered carbocyclic enimines and enones. The method starts from simple cyclic ketones and terminal olefinic amides, and relies on both the Suzuki coupling reaction and the olefin‐amide based Friedel‐Crafts type acylating reaction, a method developed by Huang and coworkers. image