Abstract

Immunolabeled tissue section of 3-day zebrafish embryo, double mutant for the tumor suppressor Rb and chromatin adaptor Rbbp4, showing programmed cell death (green), neurons (red), and nuclei (blue) in the retina and brain. From: Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis; Schultz-Rogers LE, et al. https://doi.org/10.1002/dvdy.467

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