Cover Feature: The Extended Hadamard Transform: Sensitivity‐Enhanced NMR Experiments Among Labile and Non‐Labile 1Hs of SARS‐CoV‐2‐derived RNAs (ChemPhysChem 4/2022)

Abstract

The Cover Feature illustrates how artifact-free 2D NOE correlations between labile protons can be obtained from an extended Hadamard encoding/decoding matrix, which supersedes problems in conventional Hadamard schemes. The sensitivity-enhancing abilities of extended Hadamard encoding operating in conjunction with solvent repolarization mechanisms are demonstrated on GHz NMR studies on SARS-CoV-2 RNA fragments. More information can be found in the Article by Lucio Frydman and co-workers.