Cover Feature: Regulating Antifreeze Activity through Water: Latent Functions of the Sugars of Antifreeze Glycoprotein Revealed by Total Chemical Synthesis (Chem. Eur. J. 21/2023)

Abstract

The sugar moiety of the antifreeze glycoprotein AFGP can form a unique dynamic water phase that includes disordered water molecules thereby inhibiting the freezing process. The property of this water phase seems to depend on both the structure and the number of sugar moieties. More information can be found in the Research Article by R. Okamoto, Y. Kajihara, and co-workers (DOI: 10.1002/chem.202203553).