Abstract
The cover image shows that an in situ generated amide base mediates the coupling reaction of iodoarenes and C−H heteroarenes to form a biaryl. This reaction can proceed with electron-rich, -deficient, and ortho-substituted haloarenes as well as electron-rich and -deficient C−H heteroarenes. Involvement of a radical intermediate was confirmed by radical-inhibition experiments, deuterium-labeling experiments, and EPR spectral measurements. Enhancement of the reactivity of electron-rich N-methylpyrrole was observed in the presence of electron-poor phenazine or pyrazine. More information can be found in the Full Paper by Masanori Shigeno, Yoshinori Kondo et al. on page 2082 in Issue 10, 2018 (DOI: 10.1002/ajoc.201800438).
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