Abstract
AbstractAs a natural antiviral defense system, the RNAi machinery is activated by viral dsRNA signatures, resulting in the targeted degradation of viral genomic RNAs and transcripts. Exogenously delivered insecticidal dsRNA also trigger RNAi via the same RNAi machinery, but in this case the target is the transcript of a gene essential for development or survival. As we learn more about the natural role of RNAi in viral immunity, the underlying mechanisms, and the factors that influence RNAi efficacy against agricultural pests, these studies will support the implementation of more RNAi‐based insect pest control strategies, together with the RNAi‐based control of pathogens (see pages 2–12).
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