Covariance analysis on the change of quality of life affected by percutaneous coronary intervention for patients with coronary heart disease

Abstract

To compare changes of quality of life at 3 months from baseline among patients who underwent and did not undergo percutaneous coronary intervention (PCI). Sixty one patients with coronary artery disease, who were hospitalized in Cardiology Department in March 2008, were followed-up for 3 months after being discharged. SF-36 and QOL-35 were administered before PCI and at 3 months. Patients were divided into 2 groups according to whether they underwent PCI. Changes of quality of life scores between PCI and non-PCI groups were compared using analysis of covariance. There were 24 cases in non-PCI group and 37 in PCI group. Baseline characteristics were well balanced between PCI and non-PCI groups except gender (67.6% vs. 28.6% for male, P = 0.005), history of angina (56.8% vs. 23.8%, P = 0.015), smoking history (51.4% vs.23.8%, P = 0.037) and Judkins classification of coronary artery (P = 0.001). Multivariate analysis of covariance showed that the change of life quality between non-PCI group and PCI group in 3-months after discharge had statistical differences in total scores (P = 0.044) and mental health scores (P = 0.003) of SF-36, total scores (P = 0.039) and social function scores (P = 0.007) of QOL-35. PCI can improve life quality in patients with coronary artery disease.