Covalent organic framework reinforced hollow fiber for solid-phase microextraction and determination of pesticides in foods

Abstract

A novel solid-phase micro extraction (SPME) system was constructed by immobilizing a three-dimensional hydroxyl-functionalized covalent organic framework (COF) into the wall pores of hollow fiber (HF). The extractant was sensitive to hydrogen bond acceptors contained analytes. Combined with high performance liquid chromatography (HPLC), a SPME-HPLC method was established for acetamiprid (Ace), dimethipin (Dim), and amitrole (Ami) simultaneous determination from rice and apple samples. Critical extraction parameters were optimized. The analytical method was proved to have good linearity with the linear coefficients above 0.99, satisfactory precision with the RSD less than 4.9%, desirable recovery ranged from 79.3% to 106.8%, and low limit of detection (LOD) ranged from 0.86 to 1.38 ng/g for Ace, Dim, and Ami. The explored analytical method has potentials for hydrogen bond acceptors contained pesticides sensitive and selective determination from food samples. • Covalent organic framework reinforced hollow fiber was explored. • Solid-phase micro extraction coupled with chromatographic method was applied. • Hydrogen bond acceptors contained analytes were selectively extracted. • Acetamiprid, dimethipin, and amitrole were analyzed from food samples.