Abstract
A carbohydrate‐based biosensor was prepared by functionalization of the surface of an etched fiber Bragg grating with a glucopyranosyl‐siloxane conjugate. Functionalization of the surface with the conjugate resulted in a Bragg grating shift of 24 pm. This shift in the refractive index is consistent with a theoretical shift calculated assuming monolayer coverage of the glucose conjugate on the sensor. The resulting functionalized fiber was shown to interact selectively with concanavalin A (Con A), a glucose binding protein (lectin). Exposure of the glucose‐functionalized fiber to peanut agglutinin, a galactosebinding lectin, did not result in a change of the refractive index corresponding to a binding event.
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