Abstract
Taliaferro and Taliaferro (1922) and Taliaferro (1923) have charted the course of Trypanosoma lewisi infection in rats. The presence of the parasites stimulates the production of two immune bodies: one is ablastin, the reproduction-inhibiting reaction product, and the other trypanolysin (v. Taliaferro, 1941). Failure of the reproduction-inhibiting antibody, manifested by prolongment of the reproductive phase, has been brought about experimentally by pantothenate deficiency in the host (Becker, Manresa and Johnson, 1943; Becker, Taylor, and Fuhrmeister, 1947) and by treating the host with sodium salicylate (Becker and Gallagher, 1947). The desirability of charting infections influenced with adequate but not excessive doses of salicylate and of studying the blood cell relationships in treated infections led to the present study.
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