Abstract
A coupling of carboxylic acids with ynamides and subsequent rearrangement for the synthesis of imides and amides is reported. The carboxylic acids could couple with ynamides to form α-acyloxyenamide followed by sulfonyl group migration and Mumm rearrangement to furnish the amides. Additionally, the products could be subjected to further rearrangement to deliver β-keto amides. This metal-free process represents an interesting method for chemical bonds cleavage and regeneration. Furthermore, divergent transformation of products were conducted to deliver an array of compounds.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
