Coupling Existing Client and Server Software for Integrating Waxholm Space

Abstract

Event Abstract Back to Event Coupling Existing Client and Server Software for Integrating Waxholm Space Richard Baldock1*, Daren Lee2, Seth Ruffins2 and Arthur Toga2 1 MRC, Western General Hospital, Human Genetic Unit and IGMM, United Kingdom 2 University of California Los Angeles, Laboratory of Neuro Imaging, United States The INCF Digital Atlasing Infrastructure (DAI) task force is developing a canonical three-dimensional representation of the mouse brain called Waxholm Space or WHS. The WHS model is based on high resolution (21µm3 isotropic voxels) T1, T2 and T2* MRI scans and 3D registered Nissl stained serial sections of a single C57Bl/6 male adult mouse brain. In addition to these image volumes, an indexed label image of segmented brain regions has also been generated to sub-divide the model brain. This data set acts as common space for mapping features, properties and the distribution of molecules in the brain. Such mappings results allow WHS to be a common spatial framework for accessing multiple mouse brain resources. Software for accessing and delivering online image databases have been developed independently of the INCF DAI. Rather than construct new tools de novo, straight forward extensions to the WoolzIIP server and MBAT have been written to accommodate WHS. The MouseBIRN project at LONI-UCLA and EMAP (Edinburgh Mouse Atlas Project) at the MRC-Human Genetics Unit, have brought together MBAT (MouseBIRN Atlasing Toolkit) and Woolz IIP server (a modified version of the Internet Imaging Protocol server) to deliver the the five image volumes comprising WHS mouse brain model. The Woolz IIP server allows rapid navigation and interaction with the model brain image within MBAT without the user having to download the entire set of image volumes to their local computer. MBAT’s viewer permits the user to display the model data concurrently with images from the local file system and/or other online resources. MBAT also allows registration of 2D images to the WHS model allowing the user to explore their data in the context of other resources mapped to WHS. Conference: Neuroinformatics 2010 , Kobe, Japan, 30 Aug - 1 Sep, 2010. Presentation Type: Poster Presentation Topic: Digital atlasing Citation: Baldock R, Lee D, Ruffins S and Toga A (2010). Coupling Existing Client and Server Software for Integrating Waxholm Space. Front. Neurosci. Conference Abstract: Neuroinformatics 2010 . doi: 10.3389/conf.fnins.2010.13.00133 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 18 Jun 2010; Published Online: 18 Jun 2010. * Correspondence: Richard Baldock, MRC, Western General Hospital, Human Genetic Unit and IGMM, Edinburgh, United Kingdom, sruffins@loni.ucla.edu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Richard Baldock Daren Lee Seth Ruffins Arthur Toga Google Richard Baldock Daren Lee Seth Ruffins Arthur Toga Google Scholar Richard Baldock Daren Lee Seth Ruffins Arthur Toga PubMed Richard Baldock Daren Lee Seth Ruffins Arthur Toga Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.