Abstract

Liposomes are spherically shaped phospholipid bilayers that are used to encapsulate hydrophilic or lipophilic drugs. To have efficient drug delivery by a liposome, it should be able to deliver the drug to the specific binding site, where it can affect the binding target. However, sometimes, due to the untimely drug release, this goal cannot be achieved. Therefore, the permeation rate of the drug through the liposomal membrane is important, as it affects the drug’s residence time inside the liposome.

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