Abstract
Background: The aim of our study was to demonstrate if there is any relation between the neutrophil-to-lymphocyte ratio (NLR) and mortality in severe burns Methods: The records of 366 patients who were admitted to Intensive Care Unit of Burn Center of Derince Training and Research Hospital between January 2012 and December 2015 were evaluated retrospectively. The cases who were hospitalized in service or did not require intensive care were not included in the study. The cases were divided into two groups: ex-group (Group 1) and discharge group (Group 2). In both groups demographic information such as age, gender, burn scores, neutrophil counts and lymphocyte counts during admission to the hospital were recorded. NLR is the ratio of absolute neutrophil count to the absolute lymphocyte count. Results: NLR was 10.94±7.63 in the exitus group and 5.5±5.56 in the discharged group. NLR was increased in mortality group and this value was statistically significant (p=0.00). Independent relationship between prognoses and NLR was shown with logistic regression analyses (Odds Ratio 0.895, 95% confidence interval 0.856-0.936, p=0.00). Conclusion: NLR has increased in mortality group. Our study showed that NLR is correlated with probability of mortality after severe burn injuries. Therefore, it can be used as a cheap, easily obtained and new mortality predictor in severe burns.
Highlights
The skin is the largest organ of the body
We aimed to reveal the relationship between mortality and neutrophilto-lymphocyte ratio (NLR) in cases that treated in our center
NLR is the ratio of absolute neutrophil count to the absolute lymphocyte count
Summary
The skin is the largest organ of the body While it protects the body against infections, at the same time acting as a barrier to the prevention of heat and fluid. Burns cause damaged in this barrier so the body become a clear target for infections. Burn is a type of injury to skin, or other body tissues, caused by heat, cold, chemicals, electricity, sunlight, or radiation. It is one of the most serious traumas affecting the human body. Though burn can be seen as a local disease, because of pathophysiological changes and immunological reactions in the body, it is a systemic trauma that affect the entire organism [1,2]. The aim of our study was to demonstrate if there is any relation between the neutrophilto-lymphocyte ratio (NLR) and mortality in severe burns
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