Abstract
Could Hormone Remission be Achieved in Prolactinomas with Surgery?
Highlights
Dopamine agonists (DA) are recognized as an effective medical treatmentsince the beginning 1970s[1,2]Normoprolactinemia was achievedin 59%when using bromocriptine[3].Normal PRL level can be achieved in 80-90%when using DA
Relevant systemic side effects, including vomiting, nausea, dizziness, headache have been reported in about one third of patients treated with DAs[ 4, 5]
DAs have a significant effect on other dopamine, serotonin androgenic receptors, which leads to severe neurological disorders such as postural hypotension or dyskinesia, psychosis, or mania, which provoke compulsive states[ 6,7]
Summary
Dopamine agonists (DA) are recognized as an effective medical treatmentsince the beginning 1970s[1,2]Normoprolactinemia was achievedin 59%when using bromocriptine[3].Normal PRL level can be achieved in 80-90%when using DA. Relevant systemic side effects, including vomiting, nausea, dizziness, headache have been reported in about one third of patients treated with DAs[ 4, 5]. DAs have a significant effect on other dopamine, serotonin androgenic receptors, which leads to severe neurological disorders such as postural hypotension or dyskinesia, psychosis, or mania, which provoke compulsive states[ 6,7]. In some cases these possible complications assume surgery over prolactinomas
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
