Abstract

The management of large renal stones is a challenging situation for the urologists. PCNL (percutaneous nephrolithotomy) represents the elective procedure and can be performed as monotherapy or combined with other techniques. This is a retrospective study on 75 patients diagnosed with staghorn calculi at Prof. Dr. Th. Burghele Clinical Hospital who underwent PCNL between 01.01.2018 to 31.06.2018. The aim of this study is to evaluate the correlations between the staghorn chemical composition, the stone free rate and the complication rate after surgery according to modified Clavien Dindo system of evaluation for urological procedures.

Highlights

  • The management of large renal stones is a challenging situation for the urologists

  • The first line of treatment recommended by actual guidelines is PCNL

  • Recent studies revealed that urologists have a lower rate of agreement in classifying minor complications compared to major complications based on this classification [6,8]

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Summary

Introduction

PCNL (percutaneous nephrolithotomy) represents the elective procedure and can be performed as monotherapy or combined with other techniques This is a retrospective study on 75 patients diagnosed with staghorn calculi at Prof. Even though the term of staghorn calculi is classically synonymous with infection stones, recent studies revealed changing aspects in the chemical structure of this pathology leading to an increased number of cases with a metabolic origin. This may have a notable impact on the success rate and complications management after PCNL. Some of the causes involved in calcium stones formation are: absorptive hypercalciuria, hyperparathyroidism, immobilization, excess of sodium and proteins in diet, renal tubular acidosis, bowel pathology, high purine intake, drug-induced uricosuria and genetic primary renal leak [10,11,12]

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