Could A Regulable Expression of HGF from Mesenchymal Stem Cells Improve the Ischemic Stroke Treatment?

Abstract

The study of Mesenchymal Stem Cells (MSCs) as a therapeutic strategy to treat Ischemic Stroke (IS) has been improving through decades till the point of reaching clinical trials. One of their key features for their success is their versatility regarding to the different routes through which they can be administered; MSCs can be delivered by intravenous administration since these cells are able to reach injured brain regions usually impeded by the blood brain barrier