Costus afer: A Systematic Review of Evidence-Based Data in support of Its Medicinal Relevance.

Daniel Boison,Olga Quasie,Cynthia Ayefoumi Adinortey,Michael Buenor Adinortey,Godwin Kweku Babanyinah,Gilbert Kofi Wiabo-Asabil,Rosemary Agbeko

doi:10.1155/2019/3732687

Abstract

Costus afer (C. afer) is a plant commonly known as ginger lily, spiral ginger, or bush cane. It is reportedly used in traditional medicine practice (TMP) to treat and manage many ailments including diabetes mellitus, stomach ache, arthritis, inflammation, and gout. These purported ethnomedicinal uses have triggered many research studies on the plant to amass scientific evidence. However, these research reports are scattered, and thus, this systematic review seeks to provide a comprehensive update on it covering its traditional uses, phytochemical and nutritional constituents, pharmacological activities, and toxicological effects. An online search was done using search engines such as Google Scholar, PubMed, and ScienceDirect from the period 1970 to 2019. The online search included the use of keywords, “Costus afer Ker-Gawl” or “Costus afer.” The search revealed that the stem and leaves of the plant contain substantial amounts of micronutrients and macronutrients. The leaves, stem, rhizomes, and roots of C. afer contain several steroidal sapogenins, aferosides, dioscin, and paryphyllin C and flavonoid glycoside kaempferol-3-O-α-L-rhamnopyranoside. Experimental studies on various parts of the plant showed bioactivities such as antihyperglycemic, hepatocellular protection, cardioprotection, nephroprotection, testicular protection, CNS depressant, analgesic, antiarthritis, antibacterial, and antioxidant. Based on these evident data, it is concluded that the plant could be used as an alternative and complementary therapy for many oxidative stress-related diseases, provided further scientific studies on the toxicological and pharmacological aspects are carried out.

Highlights

Daniel Boison,1 Cynthia Ayefoumi Adinortey,2 Godwin Kweku Babanyinah,1 Olga Quasie,3 Rosemary Agbeko,2 Gilbert Kofi Wiabo-Asabil,1 and Michael Buenor Adinortey 1
It is reportedly used in traditional medicine practice (TMP) to treat and manage many ailments including diabetes mellitus, stomach ache, arthritis, inflammation, and gout. ese purported ethnomedicinal uses have triggered many research studies on the plant to amass scientific evidence
Introduction e use of herbal medicine to manage or cure diseases dates back to the Stone Age. ere has been an advancement in pharmacological discoveries over the years that has resulted in the production of many synthetic drugs. is reiterates the worth of ethnomedicinal plants for drug discovery

Summary

Introduction

Daniel Boison ,1 Cynthia Ayefoumi Adinortey ,2 Godwin Kweku Babanyinah, Olga Quasie, Rosemary Agbeko ,2 Gilbert Kofi Wiabo-Asabil, and Michael Buenor Adinortey 1. Costus afer (C. afer) is a plant commonly known as ginger lily, spiral ginger, or bush cane It is reportedly used in traditional medicine practice (TMP) to treat and manage many ailments including diabetes mellitus, stomach ache, arthritis, inflammation, and gout. Experimental studies on various parts of the plant showed bioactivities such as antihyperglycemic, hepatocellular protection, cardioprotection, nephroprotection, testicular protection, CNS depressant, analgesic, antiarthritis, antibacterial, and antioxidant. Based on these evident data, it is concluded that the plant could be used as an alternative and complementary therapy for many oxidative stress-related diseases, provided further scientific studies on the toxicological and pharmacological aspects are carried out.

Methods

Results

Conclusion