Abstract
Purpose: NSAIDs are commonly used for the treatment of pain and inflammation. The major side effects of chronic NSAID use are gastrointestinal (GI) symptoms and complications. Meloxicam is a recently FDA-approved NSAID with an extensive track record in Europe that suggests that it is better tolerated than conventional NSAIDs. The objective of this study was to develop a decision model comparing meloxicam with: i) generic NSAID therapy and ii) therapy with either of two COX-2 specific NSAIDs available in the US in patients at high risk for developing a GI adverse event.
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