Abstract
Background: Cost of management of tuberculosis (TB) has high expenses from both patient and health insurance perspective. Methods: A systematic review on cost analysis of TB in children was executed in Ovid-MEDLINE for the period 1991-2011. Search terms were tuberculosis, cost and childhood. Review articles, commentaries, letters were excluded. Results: The first search resulted 156 articles, after linguistic and content screening 16 articles were considered for further analysis. The topics related to the cost-analysis were latent tuberculosis infection, BCG vaccination, cost-effectiveness of TB control program, TB screening, extrapulmonary TB, TB in resource rich and resource poor countries. Conclusion: After processing the results of the articles, it was identified that tuberculosis screening among schoolchildren and kindergarteners as well as BCG revaccination is not cost-effective in low-burden countries.
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