Abstract

BackgroundEffectiveness of Internet-based self-management in patients with asthma has been shown, but its cost-effectiveness is unknown. We conducted a cost-effectiveness analysis of Internet-based asthma self-management compared with usual care.Methodology and Principal FindingsCost-effectiveness analysis alongside a randomized controlled trial, with 12 months follow-up. Patients were aged 18 to 50 year and had physician diagnosed asthma. The Internet-based self-management program involved weekly on-line monitoring of asthma control with self-treatment advice, remote Web communications, and Internet-based information. We determined quality adjusted life years (QALYs) as measured by the EuroQol-5D and costs for health care use and absenteeism. We performed a detailed cost price analysis for the primary intervention. QALYs did not statistically significantly differ between the Internet group and usual care: difference 0.024 (95% CI, −0.016 to 0.065). Costs of the Internet-based intervention were $254 (95% CI, $243 to $265) during the period of 1 year. From a societal perspective, the cost difference was $641 (95% CI, $−1957 to $3240). From a health care perspective, the cost difference was $37 (95% CI, $−874 to $950). At a willingness-to-pay of $50000 per QALY, the probability that Internet-based self-management was cost-effective compared to usual care was 62% and 82% from a societal and health care perspective, respectively.ConclusionsInternet-based self-management of asthma can be as effective as current asthma care and costs are similar.Trial RegistrationCurrent Controlled Trials ISRCTN79864465

Highlights

  • Asthma is a chronic, inflammatory disorder of the airways clinically characterized by respiratory symptoms such as wheeze, cough, dyspnoea, chest tightness and impaired lung function [1,2]

  • In a recently conducted randomized controlled trial we have shown that Internet-based selfmanagement is feasible and provides better clinical outcomes compared to usual physician provided care with regard to asthma related quality of life, asthma control, symptom-free days and lung function [13]

  • Asthma related quality of life, asthma control and medication use were similar for the two randomization groups

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Summary

Conclusions

Internet-based self-management of asthma can be as effective as current asthma care and costs are similar. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

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