Abstract

BackgroundThe COVID-19 pandemic has caused patients to avoid seeking medical care. Provision of telemonitoring programs in addition to usual care has demonstrated improved effectiveness in managing patients with heart failure (HF).ObjectiveWe aimed to examine the potential clinical and health economic outcomes of a telemonitoring program for management of patients with HF during the COVID-19 pandemic from the perspective of health care providers in Hong Kong.MethodsA Markov model was designed to compare the outcomes of a care under COVID-19 (CUC) group and a telemonitoring plus CUC group (telemonitoring group) in a hypothetical cohort of older patients with HF in Hong Kong. The model outcome measures were direct medical cost, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratio. Sensitivity analyses were performed to examine the model assumptions and the robustness of the base-case results.ResultsIn the base-case analysis, the telemonitoring group showed a higher QALY gain (1.9007) at a higher cost (US $15,888) compared to the CUC group (1.8345 QALYs at US $15,603). Adopting US $48,937/QALY (1 × the gross domestic product per capita of Hong Kong) as the willingness-to-pay threshold, telemonitoring was accepted as a highly cost-effective strategy, with an incremental cost-effective ratio of US $4292/QALY. No threshold value was identified in the deterministic sensitivity analysis. In the probabilistic sensitivity analysis, telemonitoring was accepted as cost-effective in 99.22% of 10,000 Monte Carlo simulations.ConclusionsCompared to the current outpatient care alone under the COVID-19 pandemic, the addition of telemonitoring-mediated management to the current care for patients with HF appears to be a highly cost-effective strategy from the perspective of health care providers in Hong Kong.

Highlights

  • Heart failure (HF) is a chronic disease affecting 38 million patients worldwide, with high in-hospital mortality (6.4%), 1-year readmission rate (24%-30%), and 1-year postdischarge mortality (20%) [1,2,3,4,5]

  • A Markov decision-analytic model was designed to estimate the potential outcomes of current care under COVID-19 (CUC) with and without telemonitoring in a hypothetical cohort of older patients with heart failure (HF) in Hong Kong (Figure 1)

  • The incremental quality-adjusted life-year RR (QALY) saved by the telemonitoring group were 0.0662, with an additional cost of US $284

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Summary

Introduction

Heart failure (HF) is a chronic disease affecting 38 million patients worldwide, with high in-hospital mortality (6.4%), 1-year readmission rate (24%-30%), and 1-year postdischarge mortality (20%) [1,2,3,4,5]. This chronic cardiac disease imposes a substantial global economic burden of US $108 billion per annum (approximated in 2012) [6], which is expected to increase considerably with the aging of the population [7]. Provision of telemonitoring programs in addition to usual care has demonstrated improved effectiveness in managing patients with heart failure (HF)

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