Abstract

Musculoskeletal disorders are prevalent and expensive diseases. This study was conducted to estimate and compare the costs of illness of three musculoskeletal conditions. Patients with rheumatoid arthritis (RA), knee osteoarthritis (OA), and fibromyalgia syndrome (FMS) who referred to a rheumatologist completed questionnaires about their socio-demographic condition, clinical status, and the costs of their disease (direct costs included visits, laboratory tests, imaging, and medications; indirect costs included absence from paid work, functional inability, and paid and nonpaid household help) in the preceding year. Statistical analyses were performed by descriptive analysis, and one way ANOVA and chi-square test were used for the comparison of three groups using SPSS ver 20. A p-value

Highlights

  • Musculoskeletal disorders are prevalent and expensive diseases

  • OA of the knee was defined by American College of Rheumatology (ACR) criteria [2], and fibromyalgia syndrome (FMS) was characterized by widespread pain, tenderness, and fatigue and was diagnosed based on ACR clinical criteria [3]

  • The current study demonstrated that OA and Rheumatoid arthritis (RA) patients had the same total costs, and their costs were higher than those of FMS patients

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Summary

Introduction

Musculoskeletal disorders are prevalent and expensive diseases. Rheumatoid arthritis (RA), osteoarthritis (OA), and fibromyalgia syndrome (FMS) are three distinct chronic disorders with different epidemiologies, etiologies, and manifestations. RA is an inflammatory autoimmune disease and is classified based on 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria [1]. Osteoarthritis is believed to be a disease of old age. It may not directly lead to mortality, but it does influence the quality of life largely through pain and functional limitations. Knee OA is the most common form of this disease [2]. FMS is characterized by widespread pain, tenderness, and fatigue. Its diagnosis is based on ACR clinical criteria [3]

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