Abstract

Undifferentiated connective tissue dysplasia is one of the most common diseases of nowadays, which does not fit into the group of hereditary syndromes. This condition is diagnosed in 20–50% of the population at any age. The study aimed to correct the facial soft tissues of patients with undifferentiated connective tissue dysplasia through the cosmetic procedure of calcium hydroxylapatite injection. In 2018, a 36-year-old patient addressed the beauty salon with signs of undifferentiated connective tissue dysplasia, such as severe asymmetry of the face, infraorbital and nasolabial sulci, and thin and easily folding skin. Signs were observed from the age of 22, i.e., for 14 years. The therapy was performed using special features of the correction of facial soft tissue changes in patients with connective tissue dysplasia (CTD) using calcium hydroxylapatite-based products (Radiesse®, Merz North America, Inc., USA). Particular attention is given to the need for early correction to prevent premature skin aging related to this condition. After 14 days, a significant improvement of the patient's skin condition was noted after the passing of two procedures. Her condition was estimated as consistent with T1-2P0G0A1Zh1 P1M1K1 and corresponded to grade I age-related changes in the superficial soft tissues. The performed treatment showed high efficacy in case of mild connective tissue dysplasia diagnosis. The results showed that when collecting information from anamnesis, the diagnostic criteria for dysplasia should be considered. If the criteria are met, the cosmetological correction with collagen stimulators becomes possible.

Highlights

  • Introduction and Literature ReviewConnective tissue is one of the most widely represented tissues in the human body

  • It has been shown that, in conditions of cosmetology clinic, the correction of facial soft tissues in patients with the diagnosis of early connective tissue dysplasia is possible. us, provided a properly chosen therapy strategy and cosmetic procedures, a visit to a cosmetologist is among the mandatory actions in the early stages of connective tissue dysplasia

  • For patients with dysplasia of later stages, medical treatment is mandatory since cosmetic procedures can only give a local or masking effect but do not fundamentally change the metabolic processes occurring in the body, as is possible in the conditions of clinics [23]

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Summary

Introduction

Introduction and Literature ReviewConnective tissue is one of the most widely represented tissues in the human body. Connective tissue builds up to 50–80% of body weight. E loose connective tissue contributes to the formation of the stroma in various organs. Us, connective tissue constitutes most systems and organs of the human body, performing such important functions as protector and barrier, as well as actively participating in metabolic processes of the body. Due to the widely expressed polymorphism of connective tissue and its participation in numerous processes in the body, a large number of disorders in its functioning emerge, acquired by a person genetically or relative to the impact of adverse environmental factors. Ese disorders may contribute to the development of secondary pathologies of the organs and their systems, as well as dysplastic-dependent diseases associated with clinical and morphological disorders in the work of connective tissue.

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