Abstract

The nonparametric Sample Entropy (SE) estimator has become a standard for the quantification of structural complexity of nonstationary time series, even in critical cases of unfavorable noise levels. The SE has proven very successful for signals that exhibit a certain degree of the underlying structure, but do not obey standard probability distributions, a typical case in real-world scenarios such as with physiological signals. However, the SE estimates structural complexity based on uncertainty rather than on (self) correlation, so that, for reliable estimation, the SE requires long data segments, is sensitive to spikes and erratic peaks in data, and owing to its amplitude dependence it exhibits lack of precision for signals with long-term correlations. To this end, we propose a class of new entropy estimators based on the similarity of embedding vectors, evaluated through the angular distance, the Shannon entropy and the coarse-grained scale. Analysis of the effects of embedding dimension, sample size and tolerance shows that the so introduced Cosine Similarity Entropy (CSE) and the enhanced Multiscale Cosine Similarity Entropy (MCSE) are amplitude-independent and therefore superior to the SE when applied to short time series. Unlike the SE, the CSE is shown to yield valid entropy values over a broad range of embedding dimensions. By evaluating the CSE and the MCSE over a variety of benchmark synthetic signals as well as for real-world data (heart rate variability of three different cardiovascular pathologies), the proposed algorithms are demonstrated to be able to quantify degrees of structural complexity in the context of self-correlation over small to large temporal scales, thus offering physically meaningful interpretations and rigor in the understanding the intrinsic properties of the structural complexity of a system, such as the number of its degrees of freedom.

Highlights

  • Entropy-based structural complexity assessment is one of the most important nonlinear analysis tools for quantifying degrees of freedom in signals and systems, especially for time series.A well-known statistical entropy method, called Approximate Entropy (ApEn) [1,2], has been developed for the analysis of physiological signals, such as heart rate variability (HRV).Such an approach is based on the statistics of occurrences of similar patterns in a time series

  • We have introduced the Cosine Similarity Entropy (CSE) and the Multiscale Cosine Similarity

  • We have examined the properties of the CSE by varying the tolerance level and have found the optimal range for the tolerance to be between 0.05–0.2

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Summary

Introduction

Entropy-based structural complexity assessment is one of the most important nonlinear analysis tools for quantifying degrees of freedom in signals and systems, especially for time series. Estimation of entropy is based on the natural logarithm that gives an uncontrollable range of entropy values for small values of the proxy for the probability within the algorithm (the third issue above) To this end, the recent Fuzzy Entropy (FE), an improved version of the sample entropy has been proposed in [11,12,13,14,15] in order to provide more robust examination of the similarity between embedding vectors. Prior to introducing the proposed CSE algorithm and its multiscale version, MCSE, we shall provide an insight into the geometry of angle-based association measures of embedding vectors

Angular Distance
Properties of Angular Distance
Cosine Similarity Entropy and Multiscale Cosine Similarity Entropy
Selection of Parameters
Effect of Sample Size and Embedding Dimension
Complexity Profiles of Synthetic Noises
Complexity Profiles of Autoregressive Models
Complexity Profiles of Heart Rate Variability
Discussion and Conclusions
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