Abstract

Abstract : A single 20-minute parotid fluid sample was collected prior to, and six 20-minute samples were collected subsequent to the oral administra tion of 50-milligrams of hydrocortisone to 30 healthy young adult males. Blood was drawn be fore dosage and 2 hours thereafter. The follow ing conclusions were drawn: The serum free 17 OHCS increase after dosage was highly significant. Hydrocortisone did not exert a significant effect on parotid fluid flow rate. A highly significant increase in parotid fluid free 17-OHCS levels was found in the 40- to 60-minute sample. A significant response was elicited in all subjects within 2 hours. (Author)

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