CORRIGENDUM

Abstract

Journal of NeurochemistryVolume 107, Issue 2 p. 588-588 Free Access CORRIGENDUM This article corrects the following: The inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephalomyelitis Natalie A. Prow, David N. Irani, Volume 105Issue 4Journal of Neurochemistry pages: 1276-1286 First Published online: January 13, 2008 First published: 01 October 2008 https://doi.org/10.1111/j.1471-4159.2008.05636.xAboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat In Prow and Irani (2008), Figure 2 is incorrect. The correct version is inserted below: Figure 2Open in figure viewerPowerPoint Spinal cord expression of the main astroglial glutamate transporter, GLT-1, declines over the course of acute NSV encephalomyelitis. (a) Immunohistochemical staining (brown) shows focal loss of GLT-1 signal in the ventral grey matter of the lumbar spinal cord between early (day 2) and peak (day 7) infection. Expression returns to baseline after acute infection has subsided (day 28), despite continued paralysis in the few surviving animals at this late stage of disease (not shown). GFAP expression is not significantly altered in adjacent tissue sections, indicating the continued presence of astrocytes in spinal grey matter throughout infection. (b) A representative western blot shows that total lumbar spinal cord GLT-1 levels decline over the acute stages of NSV infection while actin expression is preserved. (c) Quantification (mean ± SEM) of GLT-1 and GFAP levels in lumbar spinal cord normalized to actin and then to levels found in uninfected control tissue shows the percent change of each protein over the course of acute stages of disease (†p < 0.05 indicating significantly reduced levels compared to those detected in uninfected control animals as determined by Friedman’s nonparametric test). Reference Prow N. A. and Irani D. N. (2008) The inflammatory cytokine, interleukin-1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephalomyelitis. J. Neurochem. 105, 1276– 1286. Volume107, Issue2October 2008Pages 588-588 FiguresReferencesRelatedInformation