Abstract
CorrigendumCorrigendumPublished Online:01 Dec 2010https://doi.org/10.1152/ajprenal.zh2-6109-corr.2010Original articleMoreSectionsPDF (387 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Volume 298, June 2010Volume 67, June 2010Pages F1297–F1305. Ferrario CM, Varagic J. The ANG-(1-7)/ACE2/mas axis in the regulation of nephron function. Am J Physiol Renal Physiol 298: , 2010.On p. F1300, the presentation of the data in Fig. 1 showing the decrease in the expression and activity of renal ACE2 in mRen2.Lewis congenics is erroneous. The error arises from inappropriate comparisons of ACE2 mRNA from different assays and a mistaken comparison of activities in the Lewis kidney and the mRen2.Lewis heart. Evidence supporting the original hypothesis for reduced renal cortical ACE2 activity was reported in both male and female mRen2.Lewis hypertensive rats and is shown in the corrected version of Fig. 1 and its revised legend below.Fig. 1.Composite of the expression of angiotensin-converting enzyme 2 (ACE2) activity in the rat kidney. In the renal cortex of a male Lewis rat, significant staining is evident in proximal tubules while there is minimal immunoreactive ACE2 in the glomerulus (left). In comparison to the Lewis normotensive rats, ACE2 activity in the renal cortex is significantly lower in both male and female hypertensive mRen2.Lewis (mRen2) rats (right). Values are means ± SE (*P < 0.05 vs. Lewis) for renal cortical ACE2 activity as adapted from Ref. 109.Download figureDownload PowerPointThis article has no references to display. Download PDF Previous Back to Top FiguresReferencesRelatedInformationRelated ArticlesThe ANG-(1–7)/ACE2/mas axis in the regulation of nephron function 01 Jun 2010American Journal of Physiology-Renal PhysiologyCited ByAngiotensin-converting enzyme 2 is reduced in Alzheimer’s disease in association with increasing amyloid-β and tau pathology25 November 2016 | Alzheimer's Research & Therapy, Vol. 8, No. 1 More from this issue > Volume 299Issue 6December 2010Pages F1515-F1515 Copyright & PermissionsCopyright © 2010 the American Physiological Societyhttps://doi.org/10.1152/ajprenal.zh2-6109-corr.2010History Published online 1 December 2010 Published in print 1 December 2010 Metrics
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