Abstract

CORRIGENDUMCorrigendumPublished Online:01 Jun 2007https://doi.org/10.1152/ajpgi.00000.2007Original articleMoreSectionsPDF (88 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Volume 292, March 2007 Volume 55, March 2007 Pages : L. Fischer, A. S. Gukovskaya, J. M. Penninger, O. A. Mareninova, H. Friess, I. Gukovsky, and S. J. Pandol, “Phophatidylinositol 3-kinase facilitates bile acid-induced Ca2+ responses in pancreatic acinar cells”Figure 6 was printed incorrectly; an extraneous trace was shown in panel A, right.The corrected figure is shown here. Fig. 6.Caffeine inhibits TLC-S induced [Ca2+]i responses in permeabilized pancreatic acinar cells. Rat pancreatic acini were resuspended in a permeabilization solution containing 10 μM digitonin. A: permeabilized acini were stimulated with 1 μM inositol (1,4,5)-trisphosphate (IP3). After [Ca2+]i reached a plateau, 20 mM caffeine was added. After 5 min of caffeine exposure (interrupted tracing), permeabilized acini were again stimulated with 1 μM IP3. B: permeabilized acini were incubated for 5 min with vehicle (top trace) or 20 mM caffeine and then stimulated with 180 μM TLC-S. Tracings are representative of 3 independent experiments. C: effect of 20 mM caffeine on the area under the curve of the [Ca2+]i response after stimulation of permeabilized acini with 180 μM TLC-S. The [Ca2+]i response to TLC-S in the absence of caffeine (i.e., in acini incubated with vehicle) was considered as 100%. Values are means ± SE from 3 tracings for the corresponding responses. *P < 0.05 compared with the [Ca2+]i response of acini stimulated by TLC-S in the absence of caffeine.Download figureDownload PowerPointThis article has no references to display. Download PDF Previous Back to Top FiguresReferencesRelatedInformationRelated articlesPhosphatidylinositol 3-kinase facilitates bile acid-induced Ca2+ responses in pancreatic acinar cells 01 Mar 2007American Journal of Physiology-Gastrointestinal and Liver Physiology More from this issue > Video Abstract Volume 292Issue 6June 2007Pages G1815-G1815 Copyright & PermissionsCopyright © 2007 the American Physiological Societyhttps://doi.org/10.1152/ajpgi.00000.2007PubMed17311895History Published online 1 June 2007 Published in print 1 June 2007 Metrics

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