Abstract

CorrigendumPublished Online:24 May 2023https://doi.org/10.1152/physiol.0009.2021_COROriginal articleMoreSectionsPDF (191 KB)Download PDF ToolsExport citationAdd to favoritesTrack citations Lee CE. Ion transporter gene families as physiological targets of natural selection during salinity transitions in a copepod. Physiology (Bethesda) 36: 335–349, 2021. doi: 10.1152/physiol.00009.2021.In FIGURE 5, the arrows for NHA point in the wrong direction. In FIGURE 5A, NHA (white) should have Na+ going into the cell and H+ going out. Corrected figure is shown below, and the article (HTML and PDF) has been updated online.FIGURE 5.Hypothetical models of ion uptake from fresh water by ionocytes in Eurytemora affinis complex populations Shown are primary transporters for energizing ion transport [V-type H+-ATPase (VHA) and NKA] and hypothetical secondary transporters for sodium uptake (NHA, Na+ channel [Nach], or NHE). A: model 1 (Wieczorek’s Model): VHA (blue) pumps H+ out of the cell and creates a proton gradient, through which Na+ is transported into the cell through an electrogenic NHA or Na+ channel. The stoichiometry of ion transport for NHA is not fully known, even for Drosophila. B: model 2: ammonia is transported out of the cell by an ammonia transporter (Rh), which then drives electroneutral NHE to export H+, and consequently import Na+. In both models, Na+ is transported to the hemolymph via NKA. Carbonic anhydrase (CA) supplies protons to VHA or NHE and HCO3− to anion exchanger (AE). The Na+/K+/2Cl– cotransporter (NKCC) might also play a role in ion uptake, but the localization of NKCC paralogs is unknown for E. affinis complex. In response to salinity change, certain paralogs of these ion transporters show evolutionary changes in gene expression and signatures of natural selection (see FIGURE 4). Alternative models have also been proposed, and not all potentially relevant ion transporters are shown. Adapted from Stern and Lee (35).Download figureDownload PowerPointThis article has no references to display. Download PDF Previous Back to Top FiguresReferencesRelatedInformation Related ArticlesIon Transporter Gene Families as Physiological Targets of Natural Selection During Salinity Transitions in a Copepod 27 Oct 2021Physiology More from this issue > Volume 38Issue 4July 2023Pages 000-000 Crossmark Copyright & PermissionsCopyright © 2023 Int. Union Physiol. Sci./Am. Physiol. Soc.https://doi.org/10.1152/physiol.0009.2021_CORPubMed37222465History Published online 24 May 2023 Published in print 1 July 2023 Metrics

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